World's End Harem - S01

Reito Mizuhara is a medical student at the National Advanced Medical School in Tokyo who comes down with a rare, deadly disease called cellular sclerosis. To get treatment, he's put into cryogenic sleep for five years. When he wakes up, he finds out that a year into his sleep, a worldwide pandemic broke out, caused by a new "Male Killer" (MK) virus that only affects males and has killed every other man on Earth. Luckily, Reito and four other men were spared during their cryosleep and are now immune to the virus. As the only men left in the world, they're expected to mate with as many women as possible to repopulate the planet. But Reito is devoted to his childhood friend and only love, Elisa Tachibana, only to learn that she went missing three years ago. While the other male survivors adjust to this new world, Reito chooses instead to search for Elisa, resist constant temptation, and look into this mysterious virus.